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Annals of Medicine and Medical Education
Volume 1, Issue 4 (December 2014), pp. 124-130

DOI: 10.12973/ejms.2014.125p

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Research Article

Published online on Apr 12, 2014

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RATIONAL DRUG USE AND COMPLIANCE IN PATIENTS WITH HIV / AIDS

Filiz OZYIGIT, Özlem ALTUNDAS AYDIN, Hayat KUMBASAR KARAOSMANOGLU, Özcan NAZLICAN, Burçin ILTER, Özlem ARIK

Abstract

Background:
According to rational drug use, the term of Compliance is to comply with all determined recommendations related to the treatment of patients and taking an active role in this process. Compliance is an indispensable component of drug therapy. furthermore, it provides the highest percentage benefits from drug on the other hand,lack of compliance causes failure of treatment . There is direct  relationship between rational drug use and compliance. In our study, our goal is to investigate the rate of compliance in HIV-infected patients initiating  antiretroviral therapy 

Methods:
In our hospital,184 HIV/AIDS patients admitted to Infectious Diseases and Clinical Microbiology  policlinic  from 1 January2006 to 31 December 2010. 142 of 184 AIDS patients  with CD4 lymphocyte count 350 mm3  and  started  HAART (highly active antiretroviral therapy)  were examined . Patient's age, gender, CD4 cell counts, antiretroviral therapy and its side effects  were analyzed from their following files retrospectively.

Conclusion:
The most important aspect of being successful in the treatment is the rational drug use. Although  all our patients were described the importance of adherence to treatment, they are not enough responsibility  to drug use (self-withdrawal drug) and compliance problem caused by adverse / side effects of drug (diarrhea, nausea, vomiting) was observed in our study.

Keywords: Rational Drug use, Compliance, HIV


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