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Annals of Medicine and Medical Education
Volume 2, Issue 1 (March 2015), pp. 1-5

DOI: 10.12973/ejms.2015.134p

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Original Article

Published online on Mar 01, 2015

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Correlation of anemia and Helicobacter pylori infection among dyspeptic patients in Kutahya region

Mustafa Cem Algin, Erim Gulcan, Zulfu Bayhan, Sezgin Zeren, Sukru Aydin Duzgun, Emel Kocak, Cengiz Kocak

Abstract

Background: The presence of Helicobacter pylori is commonly linked with anemia among dyspeptic patients. In the present study, we aimed to investigate the etiologic link between anemia and Helicobacter pylori among the general population of Kutahya.
Materials and Methods: We enrolled 1408 dyspeptic patients presenting at our institution between November 2011 and February 2015 and evaluated their complete medical records in this retrospective investigation. Helicobacter pylori colonization was identified by upper gastrointestinal endoscopic biopsy. Whole blood samples were collected at the time of endoscopy evaluated using standard blood cell counts and biochemical tests. Statistical analysis included logistic regression. Differences in proportions between experimental groups were identified using the chi-square calculation. The Student's t-test was applied to evaluate differences in continuous variables.
Results: All together, 64.4% of the patients evaluated were diagnosed with active Helicobacter pylori infection. Among infected individuals, 91.8% were anemic while only 8.2% of uninfected patients showed signs of anemia (P< 0.001). Serum hemoglobin was significantly reduced among individuals infected with Helicobacter pylori relative to uninfected patients.
Conclusions: The total rate of Helicobacter pylori colonization was high among patients with dyspepsia. The incidence of anemia was substantially greater among Helicobacter pylori infected individuals relative to uninfected patients.
Key Words: anemia, Helicobacter pylori, correlation,  dyspepsia, Kutahya region.


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