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Annals of Medicine and Medical Education
Volume 2, Issue 2 (June 2015), pp. 48-50

DOI: 10.12973/ejms.2015.141p

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Research Article

Published online on Jun 01, 2015

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25 hydroxy vitamin D3 levels in type 2 diabetic patients

Fatih Şahpaz

Abstract

Background: It has been demonstrated that vitamin D deficiency is associated with hypertension, and type 2 diabetes mellitus (T2DM). We investigate the association of 25-hydroxyvitamin D3 levels with type 2 diabetic patients. A total of 120 T2DM patients, aged between 45 and 83 years, were recruited from the outpatient clinic at DPU Evliya çelebi Education and Research Hospital from Marc 2014 to June 2014. Ninety healthy age-matched individuals constituted the control group.  Body mass index (BMI) was calculated as the weight in kilograms divided by the square of the height in meters (kg/m2).  All patients were free of diseases or medications that might interfere with their vitamin D status. This study included 120 patients with T2DM,68 females (56%) and 52 males (43%).In T2DM patients BMI(28.9±3.9), HbA1c(8.3±1.9) were significantly higher (p=<0.01) and 25(OH)D levels(9.8±8.4) were significantly lower than in controls (p=<0.01). When we made correlation analysis in diabetic patients, we found that 25OHD negatively correlated with BMI (p=<0.001, r=-0.23), HbA1c (p=<0.05, r=-0.21).  We found that vitamin D levels were significantly low in type 2 diabetics compared to non-diabetics. There was an inverse relationship between vitamin D levels and insulin resistance.Our non-diabetic population also had low 25(OH)D levels,we recommend vitamin D supplementation in our population.

Key Words: type 2 diabetes mellitus, vitamin D deficiency, Body mass index.


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